Chem. J. Chinese Universities ›› 2004, Vol. 25 ›› Issue (10): 1849.

• Articles • Previous Articles     Next Articles

Isolation and Identification of Cyclopeptides from the Roots of Schnabelia tetradonta

DOU Hui1,2, LIAO Xun2, CHEN Chang-Xiang1, PENG Shu-Lin2, ZHOU Yan2, DING Li-Sheng2   

  1. 1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China;
    2. Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China
  • Received:2003-07-03 Online:2004-10-24 Published:2004-10-24

Abstract: Four cyclopeptides were isolated from the roots of Schnabelia tetradonta, a Chinese endemic herb, through repeated column chromatography on normal and reversed phase silica gel. On the basis of spectroscopic and chemical evidence, the structures of two new cyclopeptides were elucidated as cyclo(N-Pro1-Pro2-Phe1-Phe2-Leu1-Ser-Thr-Leu2-CO)(1, schnabepeptide C) and cyclo(N-Pro1-Pro2-His-Gly-Val-Asn-Ile-Trp-CO)(2, schnabepeptide D), and other two cyclopeptides were schnabepeptide B(3) and schnabepeptide(4), respectively.

Key words: Schnabelia tetradonta, Cyclopeptide, Schnabepeptide C, Schnabepeptide D

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