Studies on the Helical Structure and Optical Rotation of Methyl Substituted Chiral Cyclic Ester Compounds

Abstract

Abstract: Four cyclic esters(1—4) and four cyclic esters substituted by methyl(5—8) were synthesized and their values of optical rotation were determined by polarimeter. The relationships of their optical active behavior and helical structure were investigated with the Rules Finding out Helical Segment combining X-ray structure image and its model structure. The variation of optical rotation value was analyzed. The experimental results accord with the quantitative analysis. It is proved that the optical ratation of compound is determined by the net optical value of the molecule and the Rules Finding Out Helical Segment can be applied to the analysis of the chiral cyclic ester.

Key words: Helical structure, Roles finding out helical segments, Optical rotation, Methyl substituted chiral cyclic ester

CLC Number:

O641.6

TrendMD:

FENG Feng . Studies on the Helical Structure and Optical Rotation of Methyl Substituted Chiral Cyclic Ester Compounds[J]. Chem. J. Chinese Universities, 2004, 25(1): 60.

References

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