Abstract: The functionalized spiro cyclopropane compounds containing multiple stereogenic centers 1a-1g were obtained in good yields with e.e.≥98%. The chemical structure of the interesting compounds 1 was established on the basis of their spectroscopic data, such as UV, IR, ¹HNMR, ¹³CNMR and MS. The spectroscopic characteristics of these title compounds are reported in detail. This result can provide an important and valuable value to recognize the structure of some complex molecules containing spiro cyclopropane skeleton with multiple chiral centers.

Key words: Spiro cyclopropane compounds containing multiple chiral centers, Stereo chemical structure, Structure characterization and resolution, Complex compound