Chem. J. Chinese Universities ›› 2001, Vol. 22 ›› Issue (S1): 111.

• Articles • Previous Articles     Next Articles

Design, Synthesis, and Biological Activities of Novel Protox Inhibitors Based on Pharmacophore Model (Ⅲ)

CHEN Kai, YANG Hua-Zheng, LI Yong-Hong   

  1. Institute of Elemento-Orgcmic Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China
  • Received:2001-07-27 Online:2001-12-31 Published:2001-12-31

Abstract:

The novel Protox inhibitors were synthesized by solid-phase organic synthesis. For biological tests, the bioassay method of Protox inhibitors was set up. The primary biological tests showed that the compounds anticipating good biological activities have Protox inhibitions in some degree.

Key words: Protox Inhibitors, Solid-phase Organic Synthesis, Biological activities

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