Chem. J. Chinese Universities ›› 2001, Vol. 22 ›› Issue (5): 788.
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JIANG Zheng-Jin, ZHANG Zhi-Chao, YIN Biao-Lin, ZHAO Guo-Feng, WANG Qin-Sun
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Abstract: Astudy has been carried out of evaluating lipophilicity of some 1-1, 2, 4-triazole compounds by RP-HPTLC. An equation that reasonably correlates partition coefficients( c lg P ) with RM0 values for 23 1-1,2,4-triazole compounds was derived and its predictive capability was tested with five 1-1,2,4-triazole compounds. It has been found that RP HPTLCcan be extensively applied to determining lipophilicity of 1-1,2,4-triazole compounds.
Key words: RP-HPTLC, 1-1,2,4-Triazole compounds, Quantitative relationship between structure and retention value, Hydrophobic parameter
CLC Number:
O657.7
TrendMD:
JIANG Zheng-Jin, ZHANG Zhi-Chao, YIN Biao-Lin, ZHAO Guo-Feng, WANG Qin-Sun . Lipophilicity Determination of Some 1-1, 2, 4-Triazole Compounds by Reversed-phase Thin Layer Chromatography[J]. Chem. J. Chinese Universities, 2001, 22(5): 788.
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http://www.cjcu.jlu.edu.cn/EN/Y2001/V22/I5/788
