Chem. J. Chinese Universities ›› 2001, Vol. 22 ›› Issue (1): 63.

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Total Synthesis of Two Neolignans for (±)-Eusiderin E and (±)-Eusiderin F

JING Xiao-Bi, GU Wen-Xin, BIE Ping-Yan, REN Xin-Feng, PAN Xin-Fu   

  1. Department of Chemistry, National Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China
  • Received:1999-11-15 Online:2001-01-24 Published:2001-01-24

Abstract: (±)-Eusiderin Eand (±)-Eusiderin F, two neolignans, were first synthesized from pyrogallol, in which route the Claisen Rearrangement was used to afford four C6_C3 units 2,6-dimethoxy-3-allyl-phenol(5), 1-(3,5-dimethoxy-4-hydroxy-phenol)propene(6), 3-methoxy-5-allyl-1,2-benzene-diol(9), 1-(5-methoxy-3,4-dihydroxy-phenol)propene(10).

Key words: Pyrogallol, Total synthesis, (±)-Eusiderin E, (±)-Eusiderin F

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