Chem. J. Chinese Universities ›› 2000, Vol. 21 ›› Issue (S1): 52.
• Analytical Sciences • Previous Articles Next Articles
ZHANG Lan1, HE Yu1, CHEN Guo-Nan1, FANG Yu-Zhi2
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Published:
Abstract:
The patients of common cold and influenza usually have some uncomfortable symptoms, such as stuffy nose, runny nose, sneezing, coughing, headache and fever. Recently the new cold medicine often contains several components, and its comprehensive effect can decrease symptoms of cold. Pseudoephedrine hydrochloride (SDP), chlorphenamine maleas (CLM), caffeine (CAF) and paracetamol (PRC) are usually existed as combination in cold medicines:SDP as a vasoconstrictor for reducing nasal congestion, CLM as a cough suppressant, and CAF and PRC as an analgesia and antipyresis. Due to matrix effects and complex ingredients, it is very difficult to detect these four components mixture simultaneously. Capillary zone electrophoresis-amperometric detection (CZE-AD) offers a rapid, simple, sensitive, low cost and high separation method for determination of above mixture.
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ZHANG Lan, HE Yu, CHEN Guo-Nan, FANG Yu-Zhi. Study of the Active Ingredients in Common Cold Medicines by Capillary Zone Electrophoresis with Amperometric Detection[J]. Chem. J. Chinese Universities, 2000, 21(S1): 52.
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http://www.cjcu.jlu.edu.cn/EN/Y2000/V21/IS1/52