Abstract:

Exogonic Acid (1) was isolated from the Brazilian tree, Ipomoea operculata. Dahlke and Graf first characterized (1) in 1964. Despite some subsequent work, it was not until 1992 that we determined the absolute stereochemistry of (1) by synthesis of enantiomers of (1) and application of enantioselective gas chromatographic technique. Here we wish to report our new seterocontrolled synthesis of (1) and its methyl ester.