Chem. J. Chinese Universities ›› 2000, Vol. 21 ›› Issue (S1): 518.
• Biological Analysis • Previous Articles Next Articles
ZHENG Xiao, LIU Liang-Xian, HUANG Pei-Qiang
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Abstract:
Previous results from this laboratory have showed that N,O-dibenzylated malimide 1 is a versatile intermediate for the asymmetric synthesis of pyrrolidines, 2-pyrrolidinons and β-hydroxy-γ-amino acids[1-4]. All the reactivities showed in synthon A have been exploited, in order to extend our studies on the (S)-malic acid-based synthetic methodology, we were interested to study the synthon B.To this end,sulfone 2 and 3,two the potential synthetic equivalent to synthon B, were prepared from malimide 1. Preliminary results showed that sulfone 2 indeed displayed the reactivity of synthon B.
TrendMD:
ZHENG Xiao, LIU Liang-Xian, HUANG Pei-Qiang. Studies On the Development of a New Chiral 2-Pyrrolidinone Synthon[J]. Chem. J. Chinese Universities, 2000, 21(S1): 518.
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http://www.cjcu.jlu.edu.cn/EN/Y2000/V21/IS1/518