Chem. J. Chinese Universities ›› 2000, Vol. 21 ›› Issue (S1): 482.

• Synthetic Sciences • Previous Articles     Next Articles

Synthesis and Antitumor Activity of Diphenylgermanium Derivatives of Heterocyclic Carboxylic Acid

YIN Han-Dong, WANG Chun-Hua, MA Chun-Lin   

  1. Department of Chemistry, Liaocheng Teachers University, Liaocheng 252059
  • Online:2000-12-31 Published:2000-12-31

Abstract:

In recent years, the diorganotin derivatives of carboxylic acid was extensively studied due to their antitumor activity. Up to now,the synthesis, characterization and biological activity of organogermanium heterocyclic carboxylate have not been studied. In this work, the sixteen new diphenylgermanium derivatives of heterocyclic carboxylic acid were synthesized by the reaction of diphenylgermanium dichloride with sodium solts of heterocyclic carboxylate in 1:1 or 1:2 molar ratio.

TrendMD: