CJCU

Chem. J. Chinese Universities ›› 2000, Vol. 21 ›› Issue (S1): 468.

• Synthetic Sciences • Previous Articles     Next Articles

Racemization of R-Naproxen Ester Using Microwave Oven

XU Yi, XIN Jia-Ying, LI Shu-Ben, WANG Lai-Lai, XIA Chun-Gu   

  1. State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000
  • Online:2000-12-31 Published:2000-12-31

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Abstract:

(S)-(+)-2-(6-methoxy-2-naphthyl) propionic acid (Naproxen) is a nonsteroidal antiinflammatory drug which belongs to the family of 2-aryl propionic acid derivatives, which is widely used as a drug for human connective tissue diseases. The physiological activity of the S-form Naproxen is 28-fold that of the R-form[1]. Hence, only the S-form is used as a drug for human diseases.

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