Abstract:

Investigation of aggregation of cholesterol vesicles is essential for the understanding of gallstones prior to the appearance of cholesterol monohydrate crystals. In this article, according to existing data based on various microscopic techniques and present data on various microstructural pathways leading to cholesterol crystal formation in bile models, we considered the bile models composed of cholesterol, bile salts and lecithin and distilled water and employed light polarization microscopy and microelectrophoresis apparatus. Concentrated isotropic solutions of bile models were diluted to induce cholesterol supersaturation and start an evolution of microstructures, leading to cholesterol crystallization.