Abstract:

Because rare earth ions have some characteristics such as narrow spectral width,long fluorescence life, large stokes shift and strongly binding with biological molecules, therefore they are usually as fluorescence probes to study nucleic acids, However the sensitivity is low. It is found that the fluorescence of Tb-nucleic acids (fish sperm DNA and yeast RNA) can increased by Sc³⁺,Y³⁺,La³⁺, Gd³⁺ and Lu³⁺, among which Gd³⁺ and Lu³⁺ have the greatest enhancement. This is a newly found co-luminescence effect.