Abstract:

The behavior of nucleic acids at charged biological interfaces (e.g. membranes) is of great importance in many biological processes. Meanwhile, the electrochemical system serves as a versatile and illuminating model of biological system, which might provide important information on properties and conformation of biomacromolecules. Electrochemical studies on DNA have attracted great interest and contributed a lot to the knowledge of structure-function relationship of DNA. However, up to now, electrochemical researches on RNA were much less explored.