Abstract:

Norfloxacin is effective antibiotics against a broad range of vegetative Gram-positive and Gram-negative bacteria. This drug is widely used as preservation in pharmaceutical formulations. In the past, norfloxacin products were determinated by using various methods, Such as spectrophotometry, HPLC and fluorescence. This paper describes an investigation of the charge transfer reaction between norfloxacin as donor and alizarin red as acceptor, leading to the determination of norfloxacin and the application of the method to suppository.