Abstract:

Molecularly imprinted polymers have been successfully utilized as tailor-made separation media possessing a predetermined selectivity in liquid chromatograph for amino derivatives, drugs and so on. To date, most of molecularly imprinted polymers have been obtained as blocks. However, it is necessary to prepare the columns of molecular-imprinted polymers by tedious, time-consuming and not economical procedures. In this paper, using R-l-(l-naphthyl)ethylamine(R-NEA) as template and methacrylic acid as functional monomer, a continuous molecularly imprinted polymer rod was prepared by in situ polymerization method,in which polymerization was carried out in a stainless steel tube full with a reaction mixture solution. Thus a column packed with molecular-imprinted polymer was obtained by a sing-step procedure without any tedious steps.