Chem. J. Chinese Universities ›› 1999, Vol. 20 ›› Issue (S1): 278.

• Chromatography and Separation Sciences • Previous Articles     Next Articles

The Comparison of Different Stationary Phases for the Analysis of Methamphtamine by Solid-phase Microextraction (SPME) and Gas Chromatography——Mass Spectrometry (GC/MS)

WANG Yi-Ru1, WANG Xiao-Ru1, Frank S. C. Lee2   

  1. 1. Department of Chemistry and the Key Laboratory of Analytical Sciences of MOE, Xiamen University, Xiamen 361005, P. R. China;
    2. Department of Chemistry, Hong Kong Baptist University, Hong Kong, P. R. China
  • Online:1999-12-31 Published:1999-12-31

Abstract:

Methamphtamine is a kind of drug used as central nervous system stimulants, which has been widely abused. The drug is analyzed both for therapeutic value and in forensic medicine and toxicology. Though liquid-liquid extraction and solid-phase extraction are two kinds of common extractant method for the analysis of methamphtamine in urine,they both need high purity solvent. Recently, Lord et.al reported the method optimization for the analysis of amphetamines in urine by head-space solid-phase microextraction. Compareing with the liquid-liquid extraction and solid-phase extraction, solid-phase microextraction has the advantages of more simple, quick operation, high efficiency and solvent free.

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