Abstract:

The chiral recognition ability of chitosan is enhanced by chemical modifications. For example, chitosans modified with phenylcarbamate or cyclodextrin were used as good stationary phases for the chiral HPLC separation of aromatic alcohols or amino acid derivatives2>, respectively. We report here the preparation of chitosans having an a -amino acid moiety in the glucosamine unit and their chiral recognition behavior toward a -amino acids under ligand-exchange chromatographic separation mode.