Chem. J. Chinese Universities ›› 1998, Vol. 19 ›› Issue (S1): 250.
• Organic Synthesis Chemistry • Previous Articles Next Articles
Liu Changling1, Liu Xiaonan1, Lei Xin1, Zhang Lixin1, Li Bin1, Steve H Shaber2, Richard M Jacobson2
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Abstract: Methoxyacrylate fungicides which came from natural product have an excellent,broad spectrum of activities, highly safety and selective to target because of their unique mode of action-inhibit mitochonidrial respiration by blocking electron transfer between cytochrome b and cytochrome c1, so more attention was paid by many companies in agrochemicals and at least 300 patents was applied until now. For the action of blocking electron transfer,some one suggests this kind of chemicals should not only work on fungi,but also on insects (sure) and weeds. Up to now,no herbicidal activity was reported. So the following compounds Ⅰ (X=O,NR,in patent:X=O,S rarely X=N) were designed and synthesized by introduced some fragment of herbicide.
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Liu Changling, Liu Xiaonan, Lei Xin, Zhang Lixin, Li Bin, Steve H Shaber, Richard M Jacobson. Synthesis of Some Novel Methoxyacrylates and Their Biological Activities[J]. Chem. J. Chinese Universities, 1998, 19(S1): 250.
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http://www.cjcu.jlu.edu.cn/EN/Y1998/V19/IS1/250