Direct Enantiomeric Resolution of Racemic μ-FcC-CHCoW-(CO)5(CpCOOC2H5) Using Amylopectin Tris(phenylcarbamate) Chiral Stationary by HPLC

Abstract

Abstract: Amylopectin tris(phenylcarbamate) was synthesized and used as the chiral stationary phase upon adsorbed over silica gel. For this purpose, amylopectin was allowed to react with an excess of phenylisocyanate in pyridine for 48 h. The carbamate was dissolved and adsorbed on silica gel which had been treated with 3-aminopropyltriethoxysilane. The weight ratio of the carbamate to the silica gel was 0.45:2.55. The racemic μ-FcC-CHCoW(CO)₅ (CpCOOC₂H₅) prepared from μ-FcC-CHCo₂.(CO)₆ and (C₂H₅OOCCp)W(CO)₃Na was resolved on this chiral stationary phase. Separation was carried out at room temperature, and methanol was used as the eluent at a flow rate of 0.5 mL/min.

Key words: HPLC, Amylopectin tris(phenylcarbamate), Dinuclear cluster

CLC Number:

O685

TrendMD:

WU Shu-Lin, ZHOU Zhi-Qiang, DING Er-Run, YIN Yuan-Qi . Direct Enantiomeric Resolution of Racemic μ-FcC-CHCoW-(CO)₅(CpCOOC₂H₅) Using Amylopectin Tris(phenylcarbamate) Chiral Stationary by HPLC[J]. Chem. J. Chinese Universities, 1998, 19(9): 1397.

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Direct Enantiomeric Resolution of Racemic μ-FcC-CHCoW-(CO)₅(CpCOOC₂H₅) Using Amylopectin Tris(phenylcarbamate) Chiral Stationary by HPLC

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