Studies on Carbohydrates (XVI)──Synthetic Study on the Precursor of Macrocyclic Compound Clemochinenoside-A

Chem. J. Chinese Universities ›› 1997, Vol. 18 ›› Issue (1): 82.

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Studies on Carbohydrates (XVI)──Synthetic Study on the Precursor of Macrocyclic Compound Clemochinenoside-A

MAO Jian-Min, CHEN Hong-Ming, CAI Meng-Shen

School of Pharmaceutical Science, Beijing Medical University, Beijing, 100083

Received:1996-01-10 Online:1997-01-24 Published:1997-01-24

Abstract

Abstract: Herein we wlsh to report the synthetic study on the precursor (10) of clemochi-nenoside-A(1), a new kind of macrocyclic glycoside, which was found in the roots of Clem-atics chinesis Osbeck (wei ling xian) that was used as Chinese herbal medicine for treatment of anthritis, arthralgia, headache and inflarnmation.The key steps were stereoselective gly-cosidation of 6 and selective mesylation of 9.Further studies are still going on,

Key words: Clemochinenoside-A, Carbohydrate, Stereoselective synthesis

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MAO Jian-Min, CHEN Hong-Ming, CAI Meng-Shen . Studies on Carbohydrates (XVI)──Synthetic Study on the Precursor of Macrocyclic Compound Clemochinenoside-A[J]. Chem. J. Chinese Universities, 1997, 18(1): 82.

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Studies on Carbohydrates (XVI)──Synthetic Study on the Precursor of Macrocyclic Compound Clemochinenoside-A

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