Studies on the Interaction Between Poly (I:C)and Cd2+

Chem. J. Chinese Universities ›› 1996, Vol. 17 ›› Issue (8): 1185.

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Studies on the Interaction Between Poly (I:C)and Cd²⁺

HUA Er-Bing¹, YANG Pin², WANG Hong-Fei², YANG Bin-Sheng², ZONH Jian-Chao³

1. Coordination Chemistry Institute, State Key Laboratory of Coordination Chemistry, Nanjing 210093;
2. Institute of Molecular Science, Shanxi University, Taiyuan 030006;
3. Institute of Biomolecules, Nankai University

Received:1995-08-04 Online:1996-08-24 Published:1996-08-24

Abstract

Abstract: The interaction of Cd²⁺ with the Aconfigurational doublestranded helix poly (I:C) was studied by rnelting curves,circular dichroism spectra,absorption spectra and fluorescence measurement.The results show that Cd²⁺ stabilizes the Aconfigurational poly (I: C) and binds to the negatively charged phosphates in poly(I: C).The binding constant of Cd²⁺ with poly(I:C) is(4.0±0.3) ×10³ (mol/L)^-1.

Key words: Ploy (I:C), Cd²⁺, A configuration, Function of phosphate

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HUA Er-Bing, YANG Pin, WANG Hong-Fei, YANG Bin-Sheng, ZONH Jian-Chao. Studies on the Interaction Between Poly (I:C)and Cd²⁺[J]. Chem. J. Chinese Universities, 1996, 17(8): 1185.

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Studies on the Interaction Between Poly (I:C)and Cd²⁺

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