Abstract: The adsorption isotherm and kinetics of simple plasma protein (human serum albumin immunoglobulin or fibrinogen)-buffer onto the surfaces of (PS-g-PEO) graft copolymers were investigated by radioiodine labelling technique.The reliability of IC1 labellingmethod was verified.It was discovered that the plateau protein adsorption amount usuallydecreased with surface PEOcontent of PS-g-PEOs increasing;the lowest protein plateau adsorption values were observed <0.25 μg.cm^-2.The "comb-like" structure of model materials might be more fit for protein-resistant property of PEO side chains.

Key words: Surface structure of polystyrene-g-poly (ethylene oxide), Protein-resistance, Isothermal adsorption of plasma proteins