Chem. J. Chinese Universities ›› 1996, Vol. 17 ›› Issue (11): 1788.

• Articles • Previous Articles     Next Articles

Studies on Synthesis and Controlled-release of Polymer Drug Using Lactic Acid-Phosphate Copolymer as Drug Carriers

FAN Chang-Lie, LI Bing, LIU Zhen-Hua, ZHUO Ren-Xi   

  1. Department of Chemistry, Wuhan University, Wuhan, 430072
  • Received:1995-10-30 Online:1996-11-24 Published:1996-11-24

Abstract: Akind of polymer drug,using 5-flurouril as model drug,lactic acid-phosphate copolymers as polymer drug carriers,was synthesized.The copolymers were characterized by 1H NMR,IRand UVspectroscopy.The contents of 5-fluorouril were determined by UVspectroscopy.The drug release in vitro of the copolymers was studied and the influence of the copolymer composition on the drug release in vitro was investigated.

Key words: Drug controlled-release, Polymer drug, Lactic acid-phosphate copolymer

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