Studies on the Activities and Synthesis of N-Substituted Pyrimidinyl or Triazinyl-3-carbamoyl-4-hydroxy-2H-1,2-benzothiazine-1,1-dioxides

Abstract

Abstract: In this paper new 3-carboxamides of 4-hydroxy-2H-1,2-benzothiazine-1,1-dioxides were synthesized by aminolysis of 4-hydroxy-2-hydro(methyl)-2H-1,2-benzothiazine-3-carboxylic acid ethyl ester-1,1-dioxides with substituted aminopyrimidines or aminotriazines.Their structures were characterized by ¹H NMR,IR,MSand elementary analysis.The biological tests indicated that the majority of these compounds showed herbicidal activity and some showed better plant-grownth regulating activity and antiinfammatory activity.

Key words: 4-Hydroxy-2-hydro(methyl)-2H-1,2-benzothiazine-3-carboxylic acid ethyl ester-1,1-dioxide, Aminolysis, Biological activity

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ZHAO Guo-Feng, ZOU Xiao-Mao, YANG Hua-Zheng. Studies on the Activities and Synthesis of N-Substituted Pyrimidinyl or Triazinyl-3-carbamoyl-4-hydroxy-2H-1,2-benzothiazine-1,1-dioxides[J]. Chem. J. Chinese Universities, 1996, 17(10): 1560.

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Studies on the Activities and Synthesis of N-Substituted Pyrimidinyl or Triazinyl-3-carbamoyl-4-hydroxy-2H-1,2-benzothiazine-1,1-dioxides

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