CJCU

Chem. J. Chinese Universities ›› 1994, Vol. 15 ›› Issue (10): 1484.

• Articles • Previous Articles     Next Articles

Intramolecular Reaction and Intramolecular Catalysis(Ⅳ)─Inductive Effect of Hydroxy Group on the Intramolecular General-base Catalyzed Hydrolysis of Ethyl 3-(2'-benzimidazolyl)-3-hydroxy Propionate by Benzimidazolyl Group

XIA Dao-Hong1, XIA Chi-Zhong2   

  1. 1. Department of Chemical Engineering, Petroleum University, Dongying, 257062;
    2. Institute of Molecular Science, Shanxi University, Taiyuan
  • Received:1993-11-24 Revised:1994-03-05 Online:1994-10-24 Published:1994-10-24

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Abstract: Benzimidazolyl group exhibits catalytic activity in the way as intramolecular general-base catalysis in the hydrolysis of 3-(2'-benzimidazolyl)-3-hydroxy propionate. Although the presence of hydroxy group in the molecule didn't change the catalytic way of benzimidazolyl group, but affected its catalytic activity evidently, Discussion for the experimental results in view of inductive effect and hydrogen bond of hydroxy group is presented.

Key words: Intramolecular catalysis, General-base catalysis, Inductive effect, Ester hydrolysis reaction

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