Chem. J. Chinese Universities ›› 1993, Vol. 14 ›› Issue (9): 1235.

• Articles • Previous Articles     Next Articles

Studies on the Synthesis of Analogues of Pseudoisocytidine

DONG Ling-Jiao, ZHANG Dong, OU YANG-Jun, WANG Yu, MA Ling-Tai, ZHANG Li-He   

  1. School of Pharmaceutical Science, Beijing Medical University, Beijing, 100083
  • Received:1992-12-13 Revised:1993-06-08 Online:1993-09-24 Published:1993-09-24

Abstract: Aseries of analogues of pseudoisocytidine were synthesized via Witting reaction.We successfully raised the yields of the key-intermediates(Ⅵ) by improving the experimental procedure, and also investigated profoundly the condensing condition of Ⅵ with some sorts of guani-dines and amidines.

Key words: Pseudoisocytidine, Wittig reaction, C-nucleoside

TrendMD: