Abstract: Anew method of factor analysis called improving iterative target transformation factor analysis (IITTFA) has been proposed.Making use of the iteration and target transformation of normal projection matrix to concentration target vector could avoid the course of inversion in general factor analysis and decrease possible amplification of experiment errors.Application of the nonlinear iterative partial least squares method (NIPLS) to solve the data matrix could simplify the procedure of general factor analysis.The method was used to assay the amounts of acetylsalicylic acid, P-acetamidophenol and caffeine containing in complex tablet of P-acetamidophenol.The average recoveries were 99.4%-100.6%.

Key words: Iterative target transformation factor analysis, Simultaneous spectrophotometric determination of multicomponents, Acetylsalicylie acid, p-Acetamidophenol, Caffeine