Chem. J. Chinese Universities ›› 1993, Vol. 14 ›› Issue (6): 791.

• Articles • Previous Articles     Next Articles

Studies on the Syntheses and Properties of N',N-(bis-(2-Chloroethyl))-O- (O',O'-dialkyl-phosphorylmethyl)-N', N'-dialkylphosphoryldiamide

CHEN Ru-Yu, ZHANG Ming, MAO Li-Juan   

  1. Institute of Elemnto-Orgatric Chemistry, Nankai University, Tianjin, 300071
  • Received:1992-09-01 Revised:1993-02-24 Online:1993-06-24 Published:1993-06-24

Abstract: Anumber of compounds with the formula (ClCH2CH2)2NP (O) NR21 (OCHRP (O)OR22) have been synthesized.Their 1H NMRspectra and some other properties are discussed.The antitumor properties of these compounds are being tested.It is found that some of them have positive results.

Key words: Antitumor agent, Phosphoramide, Phosphoryl diamide

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