Studies on the Phase Transfer Extraction of Penicillin G by Reverse Micelles

Chem. J. Chinese Universities ›› 1993, Vol. 14 ›› Issue (10): 1427.

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Studies on the Phase Transfer Extraction of Penicillin G by Reverse Micelles

WU Zi-Sheng, JIA Ying-Ping, CHU Ying, WANG Yu-Jie, LIU PeiYan, MA Zhan-Fang

Department of Chemistry, Northeast Normal University, Changchun, 130024

Received:1992-12-25 Revised:1993-03-25 Online:1993-10-24 Published:1993-10-24

Abstract

Abstract: This paper reports the extraction properties and mechanisms of a non-protein active matter penicillin Gby reverse micelles using the phase transfer technique for the first time.It is shown that the mechanisms of the phase transfer extraction of penicillin Gusing CTAB/n-octanol : chloroform(4 : 1) reverse micellar system are ion-pairing electrostatic interactions and micellar solubilisation.It is also shown that the extraction is above 90% in the pHrange from 5 to 8 in which penicillin Gis stable at room temperature.

Key words: Reverse micelle, Phase transfer, Penicillin G

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WU Zi-Sheng, JIA Ying-Ping, CHU Ying, WANG Yu-Jie, LIU PeiYan, MA Zhan-Fang. Studies on the Phase Transfer Extraction of Penicillin G by Reverse Micelles[J]. Chem. J. Chinese Universities, 1993, 14(10): 1427.

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Studies on the Phase Transfer Extraction of Penicillin G by Reverse Micelles

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