CJCU

Chem. J. Chinese Universities ›› 1992, Vol. 13 ›› Issue (8): 1080.

• Articles • Previous Articles     Next Articles

Studies on EIMS and MIKES of the Derivatives of 2,4-Diamino-5-(Substituted) Benzyl-Pyrimidine

PANG Ji-Hai1, PENG Jia-Ro1, LIANG Wei-Sheng1, WU Zhi-Ru1, ZHANG Hai-Ying1, FANG Zhao-Xia2, LI Ren-Li2   

  1. 1. Center of Analysis and Computation, Beijing Medical University, Beijing, 100083;
    2. School of Pharmacy, Beijing Medical University, Beijing
  • Received:1991-03-02 Revised:1992-04-26 Online:1992-08-24 Published:1992-08-24

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Abstract: The present paper covers the electron ionization mass spectra (EIMS) and collisional activation dissociation (CAD),mass-analyzied ion kinetic energy spectra (MIKES) of eight 2,4-diamino-5-(substituted) benzyl-pyrimidine derivatives.Accurate molecular weight of the compounds were determined by means of high resolution experiments.The rules of the cleavage of ether bonds and 2,4-diamino-5-(substituted) benzyl-pyrimidine ring in the compounds were proved by the CAD MIKES technique.The fragmentations of sample 4 were studied in detail.

Key words: 2,4-Diamino-5-(substituted)benzyl-pyrimidine, EIMS, CAD and MIKES

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