Chem. J. Chinese Universities ›› 1992, Vol. 13 ›› Issue (3): 349.

• Articles • Previous Articles     Next Articles

Studies on the Circular Dichroism of Spin-Labeled Derivatives of Podophyllotoxin

TIAN Xuan, LI Jing-xin, CHEN Yao-zu   

  1. The National Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, 730000
  • Received:1991-02-15 Online:1992-03-24 Published:1992-03-24

Abstract: The CD spectra of ten spin-labeled derivatives of podophyllotoxin were studied with CDrule of 1-aryl tetralin compounds and Snatzke's sphere rule.The relationship between the first couple and stereo-configuration and antitumor activity of these compounds were discussed.

Key words: Circular dichroism spectrum, Podophyllotoxin, Spin label, Snatzke's sphere rule

TrendMD: