Abstract: Eleven openchain azacrown ether analogues with the end groups of 4-oxyantipyrine (3_a-k) were synthesized and identified by elemental analysis and spectral data. Two methods for O-alkylation of 4-hydroxyantipyrine are reported. The phase-transfer catalytic behaviour of the new compunds is studied. It is found that these compounds used either as liquid-liquid or as solid-liquid phase-transfer catalysts have good catalytic activity.

Key words: Open-chain crown ether, 4-Hydroxyantipyrine, O-Alkylation