Chem. J. Chinese Universities ›› 1990, Vol. 11 ›› Issue (8): 894.

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Selective Reduction Alkylation of Secondary Amine with Carbonyl Compounds

Wang Ruo, Guan Yedi   

  1. Department of Chemistry, Peking University, Beijing
  • Received:1989-09-12 Online:1990-08-24 Published:1990-08-24

Abstract: Sodium hydrogen telluride was found to reduce secondary amines with carbonyl compounds to tertiary amines under mild conditions. The products of the reaction depend upon the nucleophilic character of secondary amines. As an application of this reduction, a new method for reduction alky-lation of secondary amines has been developed.

Key words: Sodium hydrogen telluride, Secondary amine, Selective reduction alkylation

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