Chem. J. Chinese Universities ›› 1989, Vol. 10 ›› Issue (5): 528.

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Polarographic Studies of Erythromycin Estolate and Its Application

Hu Yinhua, Zhang Yonghui, Xing Xiaofang   

  1. Department of Chemistry, Northwest University, Xian
  • Received:1987-07-17 Online:1989-05-24 Published:1989-05-24

Abstract: Asingle-sweep polarographic method is first presented here for the quantitative analysis of erythromycin estolate(I). Using 4 raol/L H2SO4 as the supporting electrolyte, the peak potential is -0.57 V(vs SCE). Alinear dependence between the concentration and the peak height is observed over the 0.05~10μg/mLrange with the correlation coefficient 0.9984. The adsorptive character of Iat Hg electrode is discussed. Applicability of the title method to direct measurement of Iin tablets and serum is assessed.

Key words: Erythromycin estolate, Polarographic

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