1,3,2-Oxazaphospholidine Derivatives(Ⅱ)——Studies on Synthesis and Properties of 2-Diethylamino 3-Substituted Formyl-1,3,2-Oxazaphospholidines

Abstract

Abstract: Aseries of new 2-diethylamino 3-substituted formyl-1,3,2-oxazaphospho-lidine derivatives (Ⅰ) have been prepared by the reaction of tris (diethylamino) phosphine with N-(β-hydroxyethyl) substituted amides. When (Ⅰ) was refluxed with sulfur in benzene, its 2-thione derivative (Ⅱ) was obtained. Compound(Ⅱ) can also be synthesized directly in one pot without the separation and purification of intermediate (Ⅰ). The IR, 1HNMRand MSspectra of these compounds have been discussed.

Key words: Heterocyclic compound, Oxazaphospholidine

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Yang Huazheng, Shao Jiushu, Wang Huilin, Chen Ruyu . 1,3,2-Oxazaphospholidine Derivatives(Ⅱ)——Studies on Synthesis and Properties of 2-Diethylamino 3-Substituted Formyl-1,3,2-Oxazaphospholidines[J]. Chem. J. Chinese Universities, 1988, 9(10): 1016.

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1,3,2-Oxazaphospholidine Derivatives(Ⅱ)——Studies on Synthesis and Properties of 2-Diethylamino 3-Substituted Formyl-1,3,2-Oxazaphospholidines

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