CJCU

Chem. J. Chinese Universities ›› 1987, Vol. 8 ›› Issue (8): 706.

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Quantitative Structure-Activity Study on a Series of Insecticidal O-Alkyl O-Aryl Phosphoramidothioates

Chen Ruyu, Wang Huilin, Cao Ruzhen, Zhang Zhengpu, Shao Jiushu, Zhu Lanhui, Chen Xueren, Yang Huazheng   

  1. Institute of Elemento-Organic Chemistry, Nan(?) University, Tianjin
  • Received:1986-03-26 Online:1987-08-24 Published:1987-08-24

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Abstract: 19 O-Alkyl O-aryl phosphoramidothioates were synthesized by the reaction of O-alkyl O-aryl phosphorochloridothioates with aqueous ammonia and the quantitative relationship between their structures and insecticidal activities was analyzed using physicochemical parameters of the substituents in the benzene ring by regression analysis. It was found that the electronic and hydrophobic effects of the substituents are important to the activity.

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