Abstract: Based on the activity of catalysts for hydrated sulfate in mutarotation of α-D-glucose, it was found that the relations between lgk_α,△E, △Sof mutarotation of α-D-glucose and parameters of metal ion are as follows lgk_α△E, △S=a(0.05x+0.01y)+b where x=Z^1.8/r,y=I(1+aD) Z is pesitive charge of metal ion, r is radius of metal ion in catalysts, Iis tovalent parameter,α is polarizability of metal ion, Dis parameter which depends on the electron configuration of metal ion and the d electron number.