Chem. J. Chinese Universities ›› 1987, Vol. 8 ›› Issue (3): 229.

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Studies on the Acylthiosemicarbazides and Their Related Heterocyclic Compounds (Ⅳ)--Studies of 1-Cyanoacety 1-4-aryl Thiosemicarbazides and Their 1,2,4 -triazoline-5-thione Derivative

Zhang Ziyi, Chen Limin, Feng Xiaoming, Du Youngkan   

  1. Department of Chemistry, Lanzhou University, Lanzhou
  • Received:1985-10-25 Online:1987-03-24 Published:1987-03-24

Abstract: In this paper a series of new 1-cyanoacetyl-4-aryl thiosemicarbazides (Ⅰ) have been synthesized. When aroylisothiocyanate reacted with 1-cyanoacetylhydra-zine in acetonitrile or acetone, the corresponding compound (Ⅰ) was formed respectively in yield of about 50-95%. Promoting effects of compounds (Ⅰ) on growth of plant have been tested preliminary.Compounds (Ⅰ) may be cyclized in the presence of 2N K2CO3aqueous solution to give 1,2,4-friazoline-5-thione derivatives (Ⅱ) in fairly good yield (70-90%).

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