Chem. J. Chinese Universities ›› 1987, Vol. 8 ›› Issue (10): 914.
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Chen Junjie, Yang Weiwen, Pan Xinfu, Li Yulin, Tan Zhen
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Abstract: Herein, a new synthetic method of flavanones is reported. Phenylmethylene-propanedinitriles (1), resulted from Knoevenagel condensation of aromatic aldehydes with malononitrile, have been conveniently converted into a series of flavanones by the Hoesch acylation with phloroglucinol, followed by hydrolysis, decarboxylation, and cyclization. Ten flavanones were prepared with higher yield by this new method, among them seven are new compounds.
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Chen Junjie, Yang Weiwen, Pan Xinfu, Li Yulin, Tan Zhen . A Novel Synthesis of Flavanones[J]. Chem. J. Chinese Universities, 1987, 8(10): 914.
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http://www.cjcu.jlu.edu.cn/EN/Y1987/V8/I10/914