Abstract: Salts of very weak organic bases and salts of very weak organic acids can not be titrated in aqueous solutions by classical neutralization titration methods, on account of the very weak acidity or basicity of its solution. Non-aqueous titrations as well as potentiometric titrations are used instead for analysis of drugs of this kind. Simple, rapid and accurate oscillopola-rographic titrametric methods are given for titration of these salts in aqueous solutions.