Electrochemical Detection of Penicillin Based on Titanium Nitride Nanoparticles Carbon Paste Electrode†

doi:10.7503/cjcu20160859

Abstract

Abstract:

A titanium nitride nanoparticles(TiN) modified carbon paste electrode was prepared to detect penicillin. The effects of the mass ratio of titanium nitride to graphite, electrode area, pH value and concentration of the buffer solution on the detection of penicillin were studied. With the optimized conditions, the electrode offered a minimum detection limit of 2×10^-5mol/L and a linear dynamic range of 4×10^-5—3.2×10^-3mol/L. Moreover, the detection mechanism was an adsorption action, which was revealed by the zeta potential and electrochemical impedance spectroscopy characterizations. Overall, the TiN modified carbon paste electrode shows good stability, high selectivity, excellent repeatability and a promising application in penicillin detection.

Key words: Titanium nitride, Penicillin, Carbon paste electrode, Electrochemical detection

CLC Number:

O657

TrendMD:

SUN Yiyan, LU Shanfu, WANG Haining, XIANG Yan. Electrochemical Detection of Penicillin Based on Titanium Nitride Nanoparticles Carbon Paste Electrode^†[J]. Chem. J. Chinese Universities, 2017, 38(4): 541.

Figures/Tables 7

Fig.1 CV curves of nano titanium nitride modified carbon paste electrode in 10 mmol/L K3[Fe(CN)6] and 1 mol/L NaCl solution(scan rate=20 mV/s)(A) and the linear relation ship between the electrode potential and the penicillin concentration(B)

Fig.2 Effects of the electrode area(A) and mixture ratios(B) on detection performanceInset of (A) is the picture of the electrodes with area of 1, 4 and 16 mm2, respectively. (A) a. S=1 mm2; b. S=4 mm2; c. S=16 mm2; (B) a. graphite; b. m(graphite)/m(TiN)=5∶1; c. m(graphite)/m(TiN)=2∶1; d. m(graphite)/m(TiN)=1∶1; e. m(graphite)/m(TiN)=1∶2.

Fig.3 Effects of concentration of the buffer solution(A) and pH value(B) on detection performance c(KH2PO4)/(mol·L-1): a. 0.01; b. 0.02; c. 0.1.

Fig.4 Linear calibration curve of the electrode potential to the Penicillin concentration

Fig.5 Selectivity(A) and repeatability(B) of the electrode(A) a. Penicillin; b. oxytetracycline; c. tetracycline; d. erythromycin.

Fig.6 Schematic diagram of penicillin adsorption on nano-titanium nitride

Fig.7 Zeta potential change of nano titanium nitride with the penicillin concentration(A) and the EIS of different concentrations of penicillin in 10 mmol/L potassium ferricyanide solution(B)(B) a. Bare; b. 1 mmol/L penicillin; c. 5 mmol/L penicillin; d. 10 mmol/L penicillin; e. 15 mmol/L penicillin.

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