高等学校化学学报

高等学校化学学报 ›› 1994, Vol. 15 ›› Issue (4): 524.

• 论文 • 上一篇    下一篇

磷杂螺环化合物的合成──3,9－二氢－3,9－二硫代－2,4,8,10－四氧杂－3,9－二磷杂螺环[5,5]十一烷的合成及其与α－芳基－β－硝基烯的加成反应

李玉桂1, 李建敏1, 朱雪峰1, 李建华1, 陶遵威2   

  1. 1. 南开大学元素有机化学研究所, 天津, 300071;
    2. 天津医药科学研究所
  • 收稿日期:1993-01-04 修回日期:1993-07-06 出版日期:1994-04-24 发布日期:1994-04-24
  • 通讯作者: 李玉佳,女,62岁,教授.
  • 作者简介:李玉佳,女,62岁,教授.
  • 基金资助:

    国家自然科学基金

Syntheses of Phosphaspirocyclic Complunds──3,9-2H-2,4,8,10-Tetraoxa-3,9-diphosphaspiro [5,5] undecane-3,9-disulfide and Its Addition Reaction with α-Aryl-β-Nitrostyrenes

LI Yu-Cui1, LI Jian-Min1, ZHU Xue-Feng1, LI Jian-Hua1, TAO Zun-Wei2   

  1. 1. Institute of Elemento-Organic Chemistry, Nankai University, Tianjin, 300071;
    2. Institute of Medical and Pharmceutical Science, Tianjin
  • Received:1993-01-04 Revised:1993-07-06 Online:1994-04-24 Published:1994-04-24

PDF (PC)

摘要： 本文合成了3,9-二氢-3,9-二硫代-2,4,8,10-四氧杂-3,9-二磷杂螺环-[5,5]十一烷2,研究了2在N,N-二甲基乙酰胺介质中,在氢化钠作用下与α-芳基-β-硝基烯的加成反应,得到5个新的加成产物3a-e,对2及加成物3a-e的1H NMR谱进行了归属,并得到元素分析和IR的证实。

关键词: 磷杂螺环膦酸酯, α－芳基－β－硝基烯, 加成反应

Abstract: Five new compounds with the general formula:  in which Xis H, p-MeO-, m-PhO-, p-Me2N-, have been prepared through the addition.of 3,9-2H-2,4,8,10-tetraoxa-3, 9-disulfide 2 to α-aryl-β-nitrostyrenes in the presence of NaH and DMA.The reaction mechanism and the 1H NMR of 2 and adducts 3a-e were studied.All the synthesized compounds were also confirmed by IR and elemental analysis.

Key words: Phosphaspirocyclic phosphonate, α-Aryl-β-nitrostyrene, Addition reaction

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