Dip-pen刻蚀技术直接制造蛋白质纳米阵列

高等学校化学学报 ›› 2002, Vol. 23 ›› Issue (7): 1386.

Dip-pen刻蚀技术直接制造蛋白质纳米阵列

魏莉, 洪霞, 郭薇, 白玉白, 李铁津

吉林大学化学学院, 长春 130023

收稿日期:2002-04-05 出版日期:2002-07-24 发布日期:2002-07-24
通讯作者: 白玉白(1941年生),男,教授,博士生导师,从事凝聚态物质的光物理与光化学研究.E-mail:yubai@mail.jlu.edu.cn E-mail:yubai@mail.jlu.edu.cn
基金资助:
国家自然科学基金(批准号:20073016);973项目资助

Direct Fabrication of Protein Arrays Using Dip-Pen Nanolithography

WEI Li, HONG Xia, GUO Wei, BAI Yu-Bai, LI Tie-Jin

College of Chemistry, Jilin University, Changchun 130023, China

Received:2002-04-05 Online:2002-07-24 Published:2002-07-24

摘要/Abstract

关键词: Dip-pen纳米刻蚀, 协同作用力, 蛋白质阵列

Abstract: This paper covers the first application of Dip-Pen Nanolithography(DPN) to directly write protein patterns with submicrometer dimensions onto Au substrate. Using Bovine Serum Albumin(BSA) as the ink in the DPNprocedure, we were able to utilize lateral force microscopy(LFM) images to differentiate between Au substrate and patterned area with deposited monolayers of BSA. Then the first evidence for Au_ Sbonding was reported between the gold substrate and the BSAsurface thiol groups given by the angle resolved XPSmeasurements.

Key words: DPN, Cooperation force, Protein array

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TrendMD:

魏莉, 洪霞, 郭薇, 白玉白, 李铁津. Dip-pen刻蚀技术直接制造蛋白质纳米阵列. 高等学校化学学报, 2002, 23(7): 1386.

WEI Li, HONG Xia, GUO Wei, BAI Yu-Bai, LI Tie-Jin . Direct Fabrication of Protein Arrays Using Dip-Pen Nanolithography. Chem. J. Chinese Universities, 2002, 23(7): 1386.