高等学校化学学报

高等学校化学学报 ›› 1999, Vol. 20 ›› Issue (6): 903.

• 研究简报 • 上一篇    下一篇

血液灌流用胆红素吸附剂的吸附性能研究

袁直, 魏斌, 何炳林, 顾汉卿   

  1. 1. 吸附分离功能高分子材料国家重点实验室, 南开大学高分子化学研究所, 天津 300071;
    2. 天津市泌尿外科研究所, 天津 300211
  • 收稿日期:1998-08-24 出版日期:1999-06-24 发布日期:1999-06-24
  • 通讯作者: 袁直,女,38岁,教授.
  • 作者简介:袁直,女,38岁,教授.
  • 基金资助:

    教育部重点科技项目基金(批准号:98098);天津市自然科学基金(批准号:983609711)资助课题

Studies on the Adsorption of Bilirubin by Adsorbents

YUAN Zhi, WEI Bin, HE Bing-Lin, GU Han-qing   

  1. 1. The State Key Laboratory of Functional Polymeric Materials for Adsorption Separation, The Institute of Polymer Chemistry, Nankai University, Tianjin, 300071;
    2. Tianjin Institute of Urologic Surgery, Tianjin, 300211
  • Received:1998-08-24 Online:1999-06-24 Published:1999-06-24

PDF (PC)

被引次数

23

摘要： 胆红素是一种内源性毒素.急性肝损伤时,体内胆红素的排泄受到阻碍.如何能有效地排除高浓度的胆红素,引起了各国学者的高度重视[1].文献[2,3]报道,在血液净化疗法治疗高胆红素血症中,当胆红素吸附剂上含有氨基阳离子时,可以提高其对胆红素的吸附量.

关键词: 高胆红素血症, 血液灌流, 胆红素吸附剂

Abstract: Polymeric adsorbents containing aminogroup for bilirubin were synthesized and the factors affecting the adsorption were also studied. The results show that the adsorption efficiency for bilirubin is over 80% in aqueous phosphate buffer, and 50% in the presence of bovine serum albumin within 2h. The hemocompatibility of adsorbents is good. So it is hopeful to be used in the hemoperfusion.

Key words: Bilirubinemia, Hemoperfusion, Adsorbent for bilirubin

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