高等学校化学学报

高等学校化学学报 ›› 2006, Vol. 27 ›› Issue (5): 956.doi:

• 研究论文 • 上一篇    下一篇

聚丙烯酸-b-聚(N-异丙基丙烯酰胺)嵌段共聚物的合成及其温度和pH值敏感性自组装研究

李桂英, 安英丽, 何振平, 马如江, 张望清, 史林启   

  1. 南开大学高分子化学研究所, 功能高分子材料教育部重点实验室, 天津 300071
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2006-05-10 发布日期:2006-05-10
  • 通讯作者: 史林启

Synthesis and Self-assembly of Temperature- and pH-Sensitive Diblock Copolymer of Poly(acrylic acid)-b-poly(N-isopropylacrylamide)

LI Gui-Ying, AN Ying-Li, HE Zhe-|Ping, MA Ru-Jiang, ZHANG Wang-Qing, SHI Lin-Qi*   

  1. Key Laboratory of Functional Polymer Materials of Ministry of Education, Institute of Polymer Chemistry, Nankai University, Tianjin 300071, China
  • Received:1900-01-01 Revised:1900-01-01 Online:2006-05-10 Published:2006-05-10
  • Contact: SHI Lin-Qi

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被引次数

45

摘要：

通过原子转移自由基聚合方法, 在丁酮/异丙醇混合溶剂中合成了分子量可控和分布较窄的聚丙烯酸叔丁酯-b-聚N-异丙基丙烯酰胺(PtBA-b-PNIPAM)嵌段共聚物, 用GPC和 1 H NMR对其结构进行了表征. PtBA-b-PNIPAM在甲苯中水解得到聚丙烯酸-b-聚N-异丙基丙烯酰胺(PAA-b-PNIPAM). 用动态光散射技术对PAA-b-PNIPAM在水溶液中的自组装行为随pH值和温度变化的响应进行了初步研究.

关键词: 聚丙烯酸-b-聚N-异丙基丙烯酰胺; 原子转移自由基聚合; 自组装; 环境敏感

Abstract:

Diblock copolymer of poly(t-butyl acrylate)-b-poly(N-isopropylacrylamide)(PtBA-b-PNIPAM) with designed molecular weight and narrow molecular weight distributions was synthesized by sequential atom transfer radical polymerization(ATRP) of butyl acrylate and N-isopropylacrylamide using CuCl/(1,1,4,7,7-pentamethyl diethylenetriamine(PMEDTA) and CuCl/tris(2-dimethylaminoethyl)amine(Me6TREN) as the catalyst respectively in a mixture solvent of butanone and 2-propanol. Temperature- and pH-sensitive block copolymer of poly(acrylic acid)-b-poly(N-isopropylacrylamide)(PAA-b-PNIPAM) was realized after hydrolysis of PtBA-b-PNIPAM in toluene. PAA-b-PNIPAM existed as single molecules in aqueous solution at 25 ℃ and pH>pKa of PAA. Increasing temperature above LCST of PNIPAM or decreasing pH value lower pKa of PAA respectively formed PNIPAM-core micelles or PAA-core micelles.

Key words: PAA-b-PNIPAM; Atom transfer radical polymerization(ATRP); Self-assembly; Environmental-sensitivity

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