高等学校化学学报 ›› 1999, Vol. 20 ›› Issue (S1): 277.
• Chromatography and Separation Sciences • 上一篇 下一篇
WANG Yi-Ru1, WANG Xiao-Ru1, Frank S. C. Lee2, WANG-Bo3
WANG Yi-Ru1, WANG Xiao-Ru1, Frank S. C. Lee2, WANG-Bo3
摘要:
The growth of the illegal heroin use has stimulated widespread testing for its abuse. However, since the heroin metabolizes quickly in the human body and not reliably detected in urine,its metabolites are by necessity the analytical targets for the detection of its intake. Of the metabolites of street heroin,codeine is important one. Thus,the analysis of codeine in urine also become an important application for the detection of street heroin intake. There are extensive literature on the determination of codeine in biological samples using gas chromatography/mass spectrometry(GC/MS). In those methods,the analytes were isolated by liquid-liquid or solid-phase extraction from the urine. Such procedure suffers from the requirement of high purity solvent and time consuming.
TrendMD: