高等学校化学学报 ›› 1999, Vol. 20 ›› Issue (S1): 265.

• Chromatography and Separation Sciences • 上一篇    下一篇

Separation of Naproxen Enantiomers by Chiral Stationary Phase Method of High Performance Liquid Chromatography

XU Xiu-Zhu, SHI Jie-Hua   

  1. Institute of Applied Chemistry, Zhejiang University. HangZhou 310027, P. R. China
  • 出版日期:1999-12-31 发布日期:1999-12-31

Separation of Naproxen Enantiomers by Chiral Stationary Phase Method of High Performance Liquid Chromatography

XU Xiu-Zhu, SHI Jie-Hua   

  1. Institute of Applied Chemistry, Zhejiang University. HangZhou 310027, P. R. China
  • Online:1999-12-31 Published:1999-12-31

摘要:

Separation of enantiomers is a very urgent problem in biochemical medicine and unsymmetry synthesize. High performance liquid chromatography is a powerful means in separation of enantiomers. In this study chiral stationary phase method of high performance liquid chromatography was used to separate Naproxen enantiomers, the derivative of (RS)-2-(6-methoxyl-2-naphthyl) propionic acid (namely mixed acid sample). Photodiode array detector was used to do qualitative analysis.

Abstract:

Separation of enantiomers is a very urgent problem in biochemical medicine and unsymmetry synthesize. High performance liquid chromatography is a powerful means in separation of enantiomers. In this study chiral stationary phase method of high performance liquid chromatography was used to separate Naproxen enantiomers, the derivative of (RS)-2-(6-methoxyl-2-naphthyl) propionic acid (namely mixed acid sample). Photodiode array detector was used to do qualitative analysis.

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