高等学校化学学报

高等学校化学学报 ›› 1981, Vol. 2 ›› Issue (4): 438.

• 论文 • 上一篇    下一篇

用双波长薄层扫描仪作维生素U防湿颗粒的分析

赵体慧1, 陈玉英1, 张冀1, 钱俊斌1, 于嘉临1, 单文(土典)2   

  1. 1. 南京药学院;
    2. 江苏省植物研究所
  • 收稿日期:1980-07-30 出版日期:1981-12-24 发布日期:1981-12-24

THE ANALYSIS OF ANTI-MOISTURE GRANULE OF VITAMIN U BY MEANS OF DUAL-WAVELENGTH TLC SCANNER

Zhao Tihui1, Chen Yuying1, Zhang Ji1, Qian Junbin1, Yu Jialin1, Shan Wendian2   

  1. 1. Nanjing College of Pharmacy, Nanjing;
    2. Institute of Plant Research of Jiangsu Province
  • Received:1980-07-30 Online:1981-12-24 Published:1981-12-24

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摘要： 本文用纸层析法以正丁醇-95%乙醇-甲酸-水(77:15:20:20)为展开剂,分离鉴定了维生素U防湿颗粒,并测量了各组分的Rf值。 将维生素U与其分解产物丝氨酸、甘氨酸等分离后,利用双波长薄层扫描仪与微型色谱数据处理机联用,以外标法及相对百分含量法测定含量。本法准确、灵敏、操作简便。

Abstract: Vitamin U is a commonly used combined drug for treatment of ulcer of digestive nature. Its chemical name is [(3-Amino-3-carboxypropyl)dimethyl sulfomium chloride].In this paper we have used the paper chromatography with N-butanol-95% ethanol-formic acid-water (77:15:20:20) as developing agent. We have separated and identified anti-moisture granule of vitamin U,and determined Rf value of each component.After separation of vitamin U from its decomposition products, serine, glycine etc., we availed ourselves of the dual-wavelength TLC scanner connected with the processor, and used external comparison method and relative percentage quantitative method to determine the content.This method has proved to be accurate, sensitive and simple in operation.

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