高等学校化学学报

高等学校化学学报 ›› 1986, Vol. 7 ›› Issue (2): 137.

• 研究论文 • 上一篇    下一篇

α-酰基环酮烷基化的初步探索及α-亚四氢呋喃-2-基环戊(己)酮的合成

李良助, 张旭升   

  1. 北京大学化学系
  • 收稿日期:1984-10-29 出版日期:1986-02-24 发布日期:1986-02-24

The Primary Attempt of α-Acylcycloketone Alkylation and the Synthesis of α-Furanidin-2-Ylenecyclo-Pentanone and Hexanone

Li Liangzhu, Zhang Xusheng   

  1. Department of Chemistry. Peking University, Beijing
  • Received:1984-10-29 Online:1986-02-24 Published:1986-02-24

PDF (PC)

摘要： a-4-氯丁酰基环戊酮和a-4-氯丁酰基环己酮极易发生分子内O-烷基化,分别生成a-亚四氢呋喃-2-基环戊酮和a-亚四氢呋喃-2-基环己酮,而不发生C-烷基化,相应的a-乙酰基环酮也不易发生C-烷基化,而在EtONa-EtOH中反应生成酮酸酯。

Abstract: Intramolecular alkylation of α-4-chlorobutyrylcyclopentanone and α-4-chlorobu-tyrylcyclohexanone easily occurs at oxygen to form α-furanidin-2-ylenecyclopentanone and α-furanidin-2-ylenecyclohexanone, respectively, but the corresponding C-alkyla-tion does not take place. The C-alkylation of the related α-acetylcycloketones also hardly takes place and they are converted to the corresponding keto-esters with EtONa-EtOH.

TrendMD: